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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
25.15
Human Site:
Y363
Identified Species:
46.11
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
Y363
D
P
K
S
G
S
W
Y
V
E
T
L
D
D
I
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
D228
A
M
L
K
Q
Y
A
D
K
L
E
F
M
H
I
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
Y363
D
P
K
S
G
S
W
Y
I
E
T
L
D
N
I
Dog
Lupus familis
XP_865164
414
45235
Y362
N
T
K
S
G
S
W
Y
V
E
T
L
D
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
Y386
N
T
K
R
G
S
W
Y
I
E
A
L
T
Q
V
Rat
Rattus norvegicus
P55215
452
50709
Y386
N
T
K
R
G
S
W
Y
I
E
A
L
T
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
Y313
D
T
Q
S
G
S
W
Y
I
E
T
L
D
S
V
Chicken
Gallus gallus
Q98943
424
47941
Y357
N
T
K
R
G
S
W
Y
I
E
A
L
T
T
V
Frog
Xenopus laevis
P55866
282
32106
M233
F
I
Q
S
L
C
K
M
I
K
L
Y
G
S
H
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
Y378
D
T
E
A
G
S
W
Y
V
E
N
L
D
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
T274
Y
D
L
L
T
L
L
T
F
V
N
Q
R
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
F437
N
S
A
R
G
S
W
F
I
Q
A
V
C
E
V
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
F377
N
A
E
R
G
S
W
F
I
Q
A
L
T
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
6.6
86.6
73.3
N.A.
46.6
46.6
N.A.
66.6
46.6
6.6
60
N.A.
0
N.A.
20
26.6
P-Site Similarity:
100
6.6
100
86.6
N.A.
66.6
66.6
N.A.
86.6
66.6
26.6
80
N.A.
0
N.A.
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
8
0
0
0
39
0
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
31
8
0
0
0
0
0
8
0
0
0
0
39
8
0
% D
% Glu:
0
0
16
0
0
0
0
0
0
62
8
0
0
16
0
% E
% Phe:
8
0
0
0
0
0
0
16
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
77
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
8
0
0
0
0
0
0
62
0
0
0
0
0
24
% I
% Lys:
0
0
47
8
0
0
8
0
8
8
0
0
0
0
0
% K
% Leu:
0
0
16
8
8
8
8
0
0
8
8
70
0
0
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
47
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
8
0
0
0
0
16
0
8
0
16
0
% Q
% Arg:
0
0
0
39
0
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
8
0
39
0
77
0
0
0
0
0
0
0
16
0
% S
% Thr:
0
47
0
0
8
0
0
8
0
0
31
0
31
8
8
% T
% Val:
0
0
0
0
0
0
0
0
24
8
0
8
0
8
54
% V
% Trp:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
62
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _